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What is Treximet and how does it work?
It's the only migraine treatment to combine these 2 medicines–IMITREX (sumatriptan) and prescription–strength naproxen sodium (an NSAID) — in one tablet. So it works 2 ways. TREXIMET targets the nerves and blood vessels believed to trigger a migraine, and it relieves the inflammation that can cause migraine pain.
Treximet FAQs
You should always be informed about the medicines you take or are considering taking. To help you talk to your doctor about which migraine treatment is appropriate for you, we have provided this Q & A section to help you learn more about migraines and TREXIMET.
How Should I take Treximet?
Use Treximet exactly as it was prescribed for you. Follow the instructions on your prescription label.
Never use more than the recommended dose of Treximet. Overuse of migraine headache medicine can actually make your headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks.
Take one (1) Treximet tablet as soon as you notice headache symptoms, or after an attack has already begun.
Do not crush, chew, or break the tablet. Swallow the pill whole.
You may take Treximet with or without food.
After taking a tablet: If your headache does not completely go away, or goes away and comes back, you may take a second tablet two (2) hours after the first.
You must wait at least 2 hours before taking a second tablet. Do not take more than 2 Treximet tablets in 24 hours. If your symptoms have not improved, contact your doctor before taking any more tablets.
What is RT Technology?
RT Technology is an innovative way of putting medicines in tablets, which enables the sumatriptan component to dissolve quickly after swallowing. The relationship between dissolution and effectiveness has not been established.
Will TREXIMET work for my migraines?
Clinical studies prove that TREXIMET is superior to the ingredient in IMITREX® Tablets at relieving migraine pain. It's the only migraine treatment to combine these 2 medicines—IMITREX (sumatriptan) and prescription-strength naproxen sodium (an NSAID)—in one tablet. So it works 2 ways. It targets nerves and blood vessels believed to trigger a migraine and relieves the inflammation that can cause migraine pain. Results may vary, so you should talk with your doctor to see if TREXIMET is right for you.
When should I take TREXIMET?
Although TREXIMET can be taken anytime during a migraine, headache experts agree that it's best to treat at the first sign of migraine pain.
What if I do not have TREXIMET with me when I have my first migraine symptoms?
Headache experts recommend treating at the first sign of migraine pain; however, TREXIMET may provide migraine pain relief even if migraine pain is already moderate or severe.
Are there any side effects?
In 2 clinical studies, TREXIMET had a low incidence of side effects. The most common side effects reported were dizziness, sleepiness, nausea, chest pain or discomfort, and pain or pressure in the neck or jaw. These side effects were generally mild and didn't last long. This is not a complete list of side effects. TREXIMET may also raise the risk of heart attack, stroke, serious stomach and intestinal problems such as bleeding and ulcers, and serious rash that may be fatal and occur without warning. See important safety information at the bottom of this page, and ask your doctor if TREXIMET is right for you.
Why would my doctor switch me from IMITREX?
TREXIMET is superior to the ingredient in IMITREX Tablets at relieving migraine pain. TREXIMET contains 2 medicines—IMITREX (sumatriptan) and prescription-strength naproxen sodium (an NSAID).
Important Safety Information about TREXIMET
Remember, every patient is different, and your results with TREXIMET may vary. Talk to your doctor to see if TREXIMET is right for you.
TREXIMET may increase the risk of heart attack, stroke, serious stomach and intestinal problems such as bleeding and ulcers, and serious rash that may be fatal and occur without warning. Risk of stomach and intestinal problems increases in the elderly. Do not take TREXIMET if you have a history of heart or liver disease, stroke, TIAs, problems with blood circulation, uncontrolled blood pressure, or allergic reaction to aspirin, NSAIDs, or sumatriptan; or right before or after heart surgery called coronary artery bypass graft (CABG).
Talk to your doctor before taking TREXIMET if you have risk factors for heart disease like high blood pressure, high cholesterol, smoking, obesity, diabetes, family history of heart disease, are a post-menopausal female, or male over age 40.
Talk to your doctor before taking TREXIMET if you have stomach ulcers or bleeding; chest pain, shortness of breath, irregular heartbeats; kidney problems; are pregnant, nursing, or thinking about becoming pregnant; or taking medications, especially pain relievers or antidepressants. A life-threatening problem may occur with TREXIMET, especially if used with antidepressants called SSRIs or SNRIs. Do not take TREXIMET if you have taken an MAOI antidepressant within the last 2 weeks. TREXIMET should only be used exactly as prescribed, at the lowest dose and for the shortest time possible.
*The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.
